Indigo-18 is a bio-preparation used in agriculture for treating cereal seeds prior to sowing. The preparation contains the active ingredient Kosakonia cowanii SYM00175 with a total bacterial titer not less than 1*107 CFU/ml. It is used for treating wheat and barley seeds at a rate of 2 liters per ton, once. The preparation is supplied as a water solution. The bio-preparation Indigo-18 is developed to improve seed germination and protect plants from pathogens. It is applied before sowing as a treatment for cereal crops such as winter wheat and winter barley. The preparation provides protection for seeds during the germination stage. The manufacturer of Indigo-18 is the company Indigo Ag, located in the USA. Use of the preparation is recommended strictly according to instructions to achieve maximum effect from seed treatment.