TrichoSim Bio is a bio-preparation containing Trichoderma harzianum at a concentration of 5 x 1011 CFU/ml. The preparation is used in agriculture to protect vegetable crops both in open and greenhouse conditions. Treatment is applied by irrigation: the first application is carried out 5–10 days after planting, and subsequent applications are every 30 days until the end of the vegetation period. For retail sale to the public, the preparation is used at a rate of 20 ml per 100 m². The number of applications depends on the length of the crop’s vegetation period. The preparation contains no chemical active substances and is an ecologically safe solution for plant protection.