Chlorpyrifos
Active ingredient

Chlorpyrifos

Description

Mode of action

Chlorpyrifos is a non-systemic organophosphate insecticide that acts through contact, ingestion, and vapor phase (fumigation) mechanisms.

The chemical interferes with the nervous system of insects by inhibiting the enzyme acetylcholinesterase, leading to an accumulation of acetylcholine, persistent nerve firing, paralysis, and death.

Its fast-acting nature provides an immediate knockdown effect, which is highly beneficial when insect populations reach critical levels rapidly.

The vapor action allows the active ingredient to penetrate dense crop canopies and treat soil-dwelling pests, reaching areas where direct spray contact is difficult.

It provides residual control, meaning that treated surfaces remain toxic to susceptible insects for a period ranging from one to three weeks post-application.

What it targets

It is used globally to manage a wide variety of pests across many crops including cereals, cotton, corn, fruits, and vegetables.

Primary targets include lepidopteran larvae, coleopteran adults and larvae, aphids, mites, and various soil-inhabiting pests.

It is particularly effective against tough pests like cutworms, rootworms, and stalk borers that are often protected by plant foliage.

In addition to field applications, it is utilized in professional pest control for structural and household protection against termites and cockroaches.

It helps in controlling major agricultural threats, significantly reducing crop losses caused by foliage-feeding and root-damaging organisms.

Rates and timing

Application rates depend heavily on the crop type, target pest species, and formulation concentration, typically ranging between 0.5 and 2.5 liters per hectare.

For optimal results, applications should be timed to coincide with the most vulnerable stages of the pest lifecycle, often based on scouting reports.

Equipment calibration is essential to ensure adequate coverage, particularly when targeting pests that reside on the underside of leaves or within the soil surface.

The solution should be applied when weather conditions are calm, preferably during cooler parts of the day, to minimize drift and photodegradation.

Consult the specific product label for detailed dosage instructions, as different concentrations of the active ingredient are available on the market.

Restrictions

Chlorpyrifos is highly toxic to bees, birds, and aquatic organisms, requiring strict adherence to environmental safety protocols.

Buffer zones must be maintained near water bodies and sensitive ecological areas to prevent contamination and unintended environmental impact.

Strict re-entry intervals (REI) and pre-harvest intervals (PHI) must be respected to ensure the safety of farm workers and end consumers.

Personal Protective Equipment (PPE), including chemical-resistant suits and respirators, is mandatory for all personnel handling the concentrated product.

Due to health and environmental concerns, many jurisdictions have restricted or phased out the use of chlorpyrifos, making it crucial to verify local regulations.

Regulatory

Status in the European Union

Not approved in the EU

CAS number
2921-88-2
Category (EU)
IN - Insecticide
Approved from
01.07.2006
Approval until
16.01.2020
ADI
Not appl.
ARfD
Not appl.
AOEL
Not appl.
Hazard classification (CLP)
Acute Tox. 3 - H301Aquatic Acute 1 - H400Aquatic Chronic 1 - H410
EU legislation

EU status is for reference only and does not replace national registration in your country.

Reference

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