Azoxystrobin
Active ingredient

Azoxystrobin

Description

Mode of action

Azoxystrobin belongs to the strobilurin chemical class. It acts as an inhibitor of mitochondrial respiration in fungal cells by blocking electron transfer at the cytochrome b and c1 site.

By disrupting ATP synthesis, the pathogen is deprived of energy, leading to rapid cell death. The substance possesses strong translaminar activity, quickly penetrating leaf tissues and redistributing within them.

Products containing azoxystrobin can penetrate the plant even after the spray has dried on the surface. This ensures protection for leaf areas not directly covered by the solution.

Beyond its direct fungicidal effect, azoxystrobin provides physiological benefits. It slows leaf senescence, prolonging photosynthetic activity, which significantly boosts crop yields.

The substance effectively prevents spore germination and mycelial growth, making it a vital component in prophylactic disease management programs for various crops.

What it targets

Azoxystrobin is a broad-spectrum fungicide effective against representatives of four fungal classes: Ascomycetes, Basidiomycetes, Deuteromycetes, and Oomycetes.

Primary targets include powdery mildew, septoria, rusts, fusarium, and downy mildew across a wide range of vegetable and field crops. It also inhibits late blight development.

It is widely used for cereal grains, grapes, potatoes, tomatoes, cucumbers, and onions. The list of controlled pathogens includes various leaf spots, mildews, and rot agents.

The compound shows high efficacy against downy mildew, which frequently affects cucurbits in both greenhouses and open fields.

Due to its systemic properties, azoxystrobin helps control a wide range of latent infections by suppressing their development during the early stages of plant tissue colonization.

Rates and timing

Application rates depend on the specific crop and the severity of the disease pressure. Typically, dosages vary from 0.4 to 1.0 liters of formulated product per hectare.

For maximum efficacy, treatments should be performed during periods of active crop growth before the onset of mass infection by pathogens.

Pre-harvest intervals range from 5 to 30 days depending on the crop type and the specific pesticide regulations in place.

When used in tank mixes, a physical and chemical compatibility test is essential, as many fungicides have specific requirements regarding water pH.

It is recommended not to perform more than two treatments with a strobilurin-based fungicide per season to prevent the development of resistance in target pathogens.

Restrictions

The main limitation is the risk of resistance development. Constant use of azoxystrobin alone is prohibited; it must be rotated with fungicides from different chemical classes.

The product is toxic to aquatic life, therefore spraying near fish-bearing water bodies and protected water zones is strictly prohibited.

Personnel must use personal protective equipment, including coveralls, gloves, respirators, and goggles, to prevent contact with skin or mucous membranes.

Treatment is not recommended during strong winds or if rain is expected shortly after application, as this reduces biological efficacy.

After field operations, equipment must be thoroughly cleaned to ensure that residues do not interfere with subsequent pesticide applications.

Regulatory

Status in the European Union

Approved in the EU

CAS number
131860-33-8
Approved from
01.01.2012
Approval until
31.05.2027
ADI
0.2 mg/kg bw/day
ARfD
Not appl.
AOEL
0.2 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 3 - H331Aquatic Acute 1 - H400Aquatic Chronic 1 - H410

EU status is for reference only and does not replace national registration in your country.

Reference

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