Zinc phosphide
Active ingredient Especially harmful

Zinc phosphide

Description

Mode of action

Zinc phosphide is an inorganic chemical compound classified as an acute-acting rodenticide with intestinal toxicity.

The mechanism of action relies on the chemical reaction with gastric acid in the rodent's stomach, which produces phosphine gas (hydrogen phosphide).

Phosphine acts as a potent systemic toxin that inhibits cytochrome c oxidase, an essential enzyme for cellular respiration, causing rapid metabolic collapse.

The cessation of oxygen utilization at the cellular level leads to central nervous system failure, heart damage, and quick mortality of the pest.

Due to its rapid decomposition in the presence of moisture and acidity, it is highly effective but requires careful handling to prevent unintended phosphine release.

What it targets

This compound is primarily used to control agricultural rodent populations that cause significant damage to crops and infrastructure.

Target species include common field mice, various rat species, ground squirrels, voles, and other harmful rodents found in agricultural settings.

It is widely applied in cereal crop fields, vegetable production areas, orchards, and storage facilities to prevent significant harvest losses.

By targeting the pests during periods of peak activity, zinc phosphide helps maintain the integrity of agricultural production and food safety.

The substance is effective in diverse environments, from open fields to enclosed storage structures where large rodent infestations occur.

Rates and timing

The application of zinc phosphide is typically carried out using poisoned baits, which must be formulated with precise concentrations of the active ingredient.

Baits are placed directly into rodent burrows or within protected bait stations to ensure the target animals ingest the lethal dose.

Timing is critical, and treatments are most effective when applied during seasons when natural food sources for rodents are scarce.

Applications must be systematic, ensuring adequate distribution across the infestation area to achieve comprehensive population control.

Repeated interventions should only occur after a thorough assessment of the remaining rodent population density and adherence to specific label guidelines.

Restrictions

Zinc phosphide is highly toxic to humans and non-target wildlife, necessitating rigorous safety protocols and personal protective equipment (PPE).

Precautions must be taken to prevent access by pets, livestock, and wild animals to the bait, including the use of tamper-resistant containers.

Strict environmental management is required to collect and dispose of carcasses, minimizing the risk of secondary poisoning to predators.

Personnel handling the chemical must be fully trained in safety procedures, including fire safety, as phosphine gas is flammable.

Regulatory compliance is mandatory, ensuring all applications align with local agricultural safety standards and environmental protection laws.

Regulatory

Status in the European Union

Approved in the EU

CAS number
1314-84-7
Category (EU)
RO - Rodenticide
Approved from
01.05.2011
Approval until
31.12.2026
ADI
0.042 mg/kg bw/day
ARfD
0.073 mg/kg bw
AOEL
0.042 mg/kg bw/day
Hazard classification (CLP)
Acute Tox. 2 - H300Aquatic Acute 1 - H400Aquatic Chronic 1 - H410Water-react. 1 - H260

EU status is for reference only and does not replace national registration in your country.

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