Cyazofamid
Active ingredient

Cyazofamid

Description

Mode of action

Cyazofamid is a member of the cyanoimidazole chemical class. It acts as a powerful protective and curative fungicide designed to manage oomycete pathogens.

The mechanism of action involves the inhibition of mitochondrial respiration in fungi. It specifically targets the complex bc1 in the electron transport chain, causing rapid metabolic failure.

The substance creates a strong protective film on plant surfaces. This physical barrier prevents zoospores from germinating and infecting the host tissue.

Due to its high rain-fastness, cyazofamid remains effective even under adverse weather conditions, providing long-lasting protection for crops.

It is widely recognized for its ability to suppress spore formation, which limits the secondary spread of diseases within the field.

What it targets

Cyazofamid is specifically engineered to control diseases caused by oomycetes, which are known for their high destructive potential.

The primary use is the control of late blight (Phytophthora infestans) in potatoes and tomatoes, a major threat to agricultural productivity.

It is also highly effective against downy mildew (Peronosporaceae) affecting various vegetable crops in open and protected fields.

In addition to oomycetes, the compound shows efficacy against early blight (Alternaria solani) in solanaceous crops.

Its use helps to significantly reduce inoculum pressure and ensures the healthy development of plants through the entire growing season.

Rates and timing

The timing of application is crucial, with treatments typically scheduled during phases of active crop growth or favorable conditions for disease development.

It is best used as a preventative measure applied before the appearance of visible disease symptoms on the leaves.

Treatment intervals usually range from 7 to 12 days, depending on the severity of the infection and local environmental factors.

The application rate should be determined based on the crop growth stage and the specific formulation provided by the manufacturer.

Proper calibration of spraying equipment is essential to ensure uniform coverage and optimal protection of all plant parts.

Restrictions

Avoid applying the fungicide during extreme heat, as this may decrease its efficacy and potentially harm plant foliage.

Users must strictly follow the pre-harvest interval (PHI) to ensure the safety of the harvested food products for consumers.

Always wear appropriate personal protective equipment, such as gloves and goggles, when handling or applying this chemical.

Do not allow runoff to enter water bodies, as the substance can be toxic to aquatic organisms if handled improperly.

Store in the original container in a cool, dry, and secure location away from children, pets, and unauthorized personnel.

Regulatory

Status in the European Union

Approved in the EU

CAS number
120116-88-3
Approved from
01.08.2021
Approval until
31.07.2036
ADI
0.17 mg/kg bw/day
ARfD
Not appl.
AOEL
0.045 mg/kg bw/day
Hazard classification (CLP)
Aquatic Acute 1 - H400Aquatic Chronic 1 - H410

EU status is for reference only and does not replace national registration in your country.

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