Active ingredient

Bacillus amyloliquefaciens strain MBI 600

Description

Mode of action

Bacillus amyloliquefaciens strain MBI 600 is a highly effective biological control agent used to protect crops against a variety of fungal and bacterial diseases.

The primary mechanism of action involves the rapid colonization of the plant rhizosphere, which creates a physical barrier that prevents pathogens from reaching the roots.

This strain produces secondary metabolites, including lipopeptides like surfactins and iturins, which actively degrade the cell membranes of competing harmful fungi.

In addition to direct antagonism, the bacteria trigger systemic induced resistance (ISR), priming the plant's immune system to respond faster to future infections.

By promoting vigorous root development, the strain improves nutrient and water uptake, which enhances the plant's overall vitality and resilience against environmental stress.

What it targets

The strain is specifically utilized to combat soil-borne diseases that affect seeds and seedling development during the early stages of plant growth.

It is effective against a range of common pathogens that cause rot and wilting in various agricultural crops, including vegetables, cereals, and fruits.

The use of this biological agent is a key component in integrated pest management programs, allowing growers to reduce reliance on synthetic pesticides.

  • Fusarium root rot
  • Pythium damping-off
  • Rhizoctonia solani
  • Various bacterial wilt pathogens

Prophylactic application during the seed treatment phase ensures long-term protection, establishing a healthy microbiome around the developing root system.

Rates and timing

Dosage rates vary depending on the specific formulation and the method of application, such as seed treatment, foliar spray, or soil drenching via irrigation.

When applying as a seed treatment, it is essential to ensure uniform coverage to provide a sufficient concentration of spores per individual seed.

For soil applications, the timing should coincide with the seedling emergence phase to ensure the bacteria establish themselves in the root zone immediately.

The frequency of application depends on the disease pressure and the environmental conditions, with repeat treatments often recommended for greenhouse crops.

Compatibility with other fertilizers is generally high, though growers should avoid mixing with antimicrobial agents that could inhibit the efficacy of the strain.

Restrictions

Environmental conditions, particularly soil temperature and moisture levels, play a critical role in the growth and efficacy of MBI 600 populations.

Application should be avoided during periods of high UV exposure, as sunlight can significantly reduce the viability of the bacterial spores on exposed surfaces.

The storage of the product requires cool, dry conditions away from direct sunlight to maintain the high colony-forming unit counts required for effectiveness.

Mixing the product with potent chemical pesticides should be strictly avoided unless specifically labeled as compatible to ensure the biological agent remains active.

While the product is considered environmentally friendly, standard safety precautions should still be taken when handling large quantities to avoid dust inhalation.

Regulatory

Status in the European Union

Approved in the EU

Approved from
16.09.2016
Approval until
16.09.2026
ADI
Not appl.
ARfD
Not appl.
AOEL
Not appl.

EU status is for reference only and does not replace national registration in your country.